The CellChip Group is part of the Competence Center for Mechanobiology (Kompetenzzentrum MechanoBiologie), which was founded by several organizations in Austria and Czech Republic. The competence center is funded by the European Regional Development Fund in the Interreg V-A Austria – Czech Republic programme (project number: ATCZ133).
The goal is to combine interdisciplinary approaches from medicine and technology to investigate the influence of mechanical stimuli on tissue regeneration. We jointly aim at identifying key factors in mechanotransduction in response to fluid shear stress, compression and stretching on regeneration processes.
The aim of the project is to shed light on the impact of increased mechanical loading on soft and hard tissues such as vasculature, connective tissue, and bone and as well as cartilage and tendons. We are currently developing various organ-on-a-chip devices containing integrated mechanical actuators that are capable of applying defined compression profiles.
The aim of the project is to study tissue regeneration during ageing and inflammatory processes in response to mechanical stress. In particular we are interested in developing a traumatic brain injury model.