Smart Implants: Next generation medical devices for personalized medicine
Endosseous implants support bone healing and permit early musculoskeletal loading shortly after trauma surgery. Monitoring of osseous healing by X-ray imaging is limited due to high energy absorption within the patient’s body and exhibits reduced resolution at metallic surfaces.
To overcome this technological limitation we have developed an implantable biosensor capable of monitoring implant integration, stability and patient-dependent bone healing kinetics and has four discernable features.
Implantable biosensors: Transplant-rejection monitoring
Every transplanted tissue and solid organ bears the risk of rejection, which can finally result in the loss of the transplant with falling back into disability or even death.
To overcome the medical risks associated with obtaining heart tissue biopsies to identify organ rejection episodes, we are currently developing an titanium-dioxide coated implantable biosensors for transplant rejection monitoring.
Detection of early stages of rejection and continuous monitoring can prevent severe organ impairment or even loss of function.