We have established a multifunctional nanobiointerface inside microfluidic devices for selective blood cell capture, enrichment and phenotyping applications that features both excellent antifouling properties and high antibody activity.
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We have developed a novel method for cell cultivation in a micro-sized polymer device under anoxic (absence of oxygen) conditions, where neither additional supplements (oxygen scavengers) nor gas supply is needed. The dissolved oxygen is scavenged by a modified thiol-ene-epoxy polymer, while the scavenging rate is adjustable by fabrication process and channel geometry.
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A lab-on-a-chip capable of mechanically inducing circular cell-free areas within confluent cell layers.
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We are currently developing a microfluidic live cell microarray containing integrated optical microsensors to continuously and non-invasively monitor oxygen consumption and acidification rates of various cell types in the absence and presence of nanoparticles.
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Generation of multi-cellular spheroids inside microfluidic devices to assess drug diffusivity.
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Development of a disposable, self-powered biosensing microsystem based on the integraton of a biofuel cell connected to a microsensor array and readout for point-of-care diagnostics of biofluids including urine, saliva and blood.
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Transplant-rejection monitoring: Every transplanted tissue and solid organ bears the risk of rejection, which can finally result in the loss of the transplant with falling back into disability or even death. To overcome the medical risks associated with obtaining heart tissue biopsies to identify organ rejection episodes, we are currently developing an titanium-dioxide coated implantable […]
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Next generation medical devices for personalized medicine: Endosseous implants support bone healing and permit early musculoskeletal loading shortly after trauma surgery.
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